Yes, I work from home, because I have health problems. I can’t travel or move to another town/country. But it means I’m at my desk 20h/day ! Which is truly an advantage for the employers who were smart enough to trust me and hire me, as you can read in their recommendations letters. I’m an extremely dedicated workaholic, always available and very reactive.
Me being homebound didn’t prevent me to write thousands of papers, 15 books, make many websites/bogs and work in the Marketing team of a European company.